NDUFA9

Across TCGA patient cohorts, NDUFA9 mutation is significantly associated with the total protein of many other genes, with 22 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NDUFA9-associated genes across cancer lineages are Syk, ASNS, and Caspase-7-cleavedD198. Each is linked with NDUFA9 in more than 1 cancer types. Because this analysis shows association rather than direction, both NDUFA9-to-partner and partner-to-NDUFA9 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Syk grouped by NDUFA9-low versus NDUFA9-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NDUFA9→partner) and Y-score (partner→NDUFA9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Syk →	+0.363	+1.598	.026	.044	3	2
UCEC	ASNS →	+0.427	+2.321	.006	.034	3	2
UCEC	Caspase-7-cleavedD198 →	+0.804	+2.479	.001	.010	3	2
UCEC	14-3-3_beta →	-0.115	-2.295	.008	.033	3	1
UCEC	EGFR_pY1068 →	-0.289	-2.115	.008	.019	3	1
UCEC	eIF4E →	+0.197	+2.807	.032	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 22 associations by consensus.

Syk by NDUFA9 expression — UCEC

Explore this box plot interactively →