NDUFA8

Across TCGA patient cohorts, NDUFA8 mutation is significantly associated with the total protein of many other genes, with 2 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NDUFA8-associated genes across cancer lineages are p90 RSK and Tuberin. Each is linked with NDUFA8 in more than 1 cancer types. Because this analysis shows association rather than direction, both NDUFA8-to-partner and partner-to-NDUFA8 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, p90 RSK grouped by NDUFA8-low versus NDUFA8-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NDUFA8→partner) and Y-score (partner→NDUFA8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	p90 RSK →	+0.194	+2.817	.036	.036	2	1
UCEC	Tuberin →	+0.279	+3.009	.032	.019	2	1

Each partner links to its Q-omics profile. Showing the 2 strongest of 2 associations by consensus.

p90 RSK by NDUFA8 expression — UCEC

Explore this box plot interactively →