NDUFA6

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, NDUFA6 mutation is significantly associated with the RNA expression of many other genes, with 50 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NDUFA6-associated genes across cancer lineages are USP17L16P, RNA5SP524, and RNU6-1317P. Each is linked with NDUFA6 in more than 1 cancer types. Because this analysis shows association rather than direction, both NDUFA6-to-partner and partner-to-NDUFA6 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NDUFA6→partner) and Y-score (partner→NDUFA6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
SKCMUSP17L16P →+0.029+7.816<.001.00831
HNSCRNA5SP524 →+0.273+7.954<.001.00831
HNSCRNU6-1317P →+2.093+7.954<.001.00831
HNSCMIR548BA →+0.363+7.954<.001.00831
HNSCMTND1P12 →+0.224+7.954<.001.00831
HNSCTTTY4B →+0.029+7.954<.001.00831
Each partner links to its Q-omics profile. Showing the 6 strongest of 50 associations by consensus.

Exploration