NDUFA5P6

Across TCGA pan-cancer cohorts, NDUFA5P6 RNA is linked to patient survival in 18 of 34 cancer types, making it the most broadly survival-associated NDUFA5P6 data layer.

The strongest signal is observed in kidney chromophobe (KICH), where higher NDUFA5P6 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated NDUFA5P6 expression acts as an unfavorable survival marker, although some lineages such as THCA and OV show a favorable association.

KICH, THCA, and ACC are the cancer types where NDUFA5P6 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KICH	OS	Tertile	III,IV	0.162	0.763	<.001	81	view →
THCA	OS	Tertile	All	1.000	0.915	.010	55	view →
ACC	DFS	Tertile	IV	0.010	0.383	<.001	54	view →
BLCA	DFS	Tertile	III,IV	0.256	0.592	<.001	45	view →
KIRC	OS	Tertile	All	0.726	0.819	.007	36	view →
BRCA	DFS	Tertile	II,III,IV	0.886	0.946	.010	36	view →
OV	OS	Tertile	All	0.911	0.812	<.001	36	view →
COAD	OS	Tertile	IV	0.039	0.660	<.001	36	view →
PAAD	OS	Tertile	II,III,IV	0.241	0.461	.011	34	view →
SKCM	DFS	Tertile	IV	0.035	0.476	.002	33	view →
SARC	OS	Tertile	All	0.223	0.647	<.001	30	view →
CHOL	DFS	Tertile	All	0.858	0.315	.017	21	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 18 lineages.

NDUFA5P6–KICH (OS)

Open the KICH breakdown →