Across TCGA patient cohorts, NDUFA4L2 mutation is significantly associated with the RNA expression of many other genes, with 343 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NDUFA4L2-associated genes across cancer lineages are DLAT, RAD17, and VPS37A. Each is linked with NDUFA4L2 in more than 1 cancer types. Because this analysis shows association rather than direction, both NDUFA4L2-to-partner and partner-to-NDUFA4L2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NDUFA4L2→partner) and Y-score (partner→NDUFA4L2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	DLAT →	+0.662	+3.202	.008	.009	3	1
UCEC	RAD17 →	+0.599	+3.459	.002	.005	3	1
UCEC	VPS37A →	+0.630	+3.470	.005	.003	3	1
UCEC	ABHD3 →	+0.758	+3.191	.004	.009	3	1
UCEC	CLDND2 →	+0.757	+3.470	<.001	.003	3	1
UCEC	DBF4B →	+0.622	+3.459	.002	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 343 associations by consensus.

Exploration

NDUFA4L2 survival (RNA) · tumor vs normal (RNA) · all NDUFA4L2 data types