Across TCGA patient cohorts, NDUFA4 mutation is significantly associated with the RNA expression of many other genes, with 195 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NDUFA4-associated genes across cancer lineages are RNU4ATAC7P, FABP5P5, and GBP5. Each is linked with NDUFA4 in more than 1 cancer types. Because this analysis shows association rather than direction, both NDUFA4-to-partner and partner-to-NDUFA4 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NDUFA4→partner) and Y-score (partner→NDUFA4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	RNU4ATAC7P →	+0.311	+7.741	<.001	.009	3	2
UCEC	FABP5P5 →	+0.126	+3.613	.001	<.001	3	2
UCEC	GBP5 →	+1.164	+3.332	.006	.005	3	1
UCEC	SLAMF6 →	+0.998	+3.332	.001	.005	3	1
UCEC	PYHIN1 →	+0.733	+3.332	<.001	.005	3	1
UCEC	CTLA4 →	+1.101	+3.364	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 195 associations by consensus.

Exploration

NDUFA4 survival (RNA) · tumor vs normal (RNA) · all NDUFA4 data types