Across TCGA patient cohorts, NDUFA4 mutation is significantly associated with the immune_cell of many other genes, with 3 significant associations in total. GBM shows the largest number of these associations.

The most reproducible NDUFA4-associated genes across cancer lineages are CD4+ Tem, CD8+ T-cells, and CD8+ naive T-cells. Each is linked with NDUFA4 in more than 1 cancer types. Because this analysis shows association rather than direction, both NDUFA4-to-partner and partner-to-NDUFA4 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NDUFA4→partner) and Y-score (partner→NDUFA4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	CD4+ Tem →	+0.034	+5.624	<.001	.039	3	1
GBM	CD8+ T-cells →	+0.008	+5.614	<.001	.039	3	1
UCEC	CD8+ naive T-cells →	+0.038	+2.212	.007	.034	2	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

Exploration

NDUFA4 survival (RNA) · tumor vs normal (RNA) · all NDUFA4 data types