Across TCGA cell cohorts, NDUFA4 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,537 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible NDUFA4-associated GO terms across cancer lineages are Positive regulation of isotype switching to IgG isotypes, Proton motive force-driven ATP synthesis, and Aerobic electron transport chain. Each is linked with NDUFA4 in more than 13 cancer types. Because this analysis shows association rather than direction, both NDUFA4-to-partner and partner-to-NDUFA4 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NDUFA4→partner) and Y-score (partner→NDUFA4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Myeloma	Positive regulation of isotype switching to IgG isotypes →	+0.143	+1.069	.006	.003	3	14
UPPER_AERODIGESTIVE_TRACT	Proton motive force-driven ATP synthesis →	+0.130	+1.233	<.001	<.001	3	13
UPPER_AERODIGESTIVE_TRACT	Aerobic electron transport chain →	+0.115	+1.201	<.001	<.001	3	13
UPPER_AERODIGESTIVE_TRACT	Proton motive force-driven mitochondrial ATP synthesis →	+0.134	+1.320	<.001	<.001	3	13
UPPER_AERODIGESTIVE_TRACT	Oxidative phosphorylation →	+0.114	+1.257	<.001	<.001	3	13
UPPER_AERODIGESTIVE_TRACT	Mitochondrial electron transport, NADH to ubiquinone →	+0.129	+1.229	<.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,537 associations by consensus.

Exploration

NDUFA4 survival (RNA) · tumor vs normal (RNA) · all NDUFA4 data types