NDUFA1

Across TCGA pan-cancer cohorts, NDUFA1 mass-spec protein is linked to patient survival in 4 of 34 cancer types, making it a survival-associated NDUFA1 data layer compared with 26 for mass-spec protein and 2 for mutation status.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher NDUFA1 mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated NDUFA1 expression acts as an unfavorable survival marker, although some lineages such as HNSC and LSCC show a favorable association.

LUAD, HNSC, and LSCC are the cancer types where NDUFA1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	OS	Median	All	0.619	1.000	.012	8	view →
HNSC	OS	Median	IV	0.873	0.630	.019	3	view →
LSCC	DFS	Tertile	II,III,IV	1.000	0.356	.024	2	view →
CCRCC	OS	Median	III,IV	0.657	1.000	.044	1	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

NDUFA1–LUAD (OS)

Open the LUAD breakdown →