NDST3

Across TCGA cell cohorts, NDST3 mutation is significantly associated with the RNA expression of many other genes, with 72 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible NDST3-associated genes across cancer lineages are OR6C2, HTR1A, and OR5V1. Each is linked with NDST3 in more than 1 cancer types. Because this analysis shows association rather than direction, both NDST3-to-partner and partner-to-NDST3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR6C2 grouped by NDST3-low versus NDST3-high in STOMACH.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NDST3→partner) and Y-score (partner→NDST3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	OR6C2 →	+0.020	+5.285	<.001	.003	3	2
LUNG_NSCLC_LUAD	HTR1A →	+0.010	+4.681	<.001	.003	3	2
LUNG_NSCLC_LUAD	OR5V1 →	+0.022	+3.947	<.001	.004	3	2
BLOOD_Leukemia	LGI1 →	+0.096	+4.539	<.001	.007	3	1
BLOOD_Leukemia	FAM71B →	+0.016	+5.060	<.001	.001	3	1
BLOOD_Leukemia	OR10H2 →	+0.014	+4.969	.002	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 72 associations by consensus.

OR6C2 by NDST3 expression — STOMACH

Explore this box plot interactively →