NDST1-AS1

Across TCGA pan-cancer cohorts, NDST1-AS1 RNA is linked to patient survival in 22 of 34 cancer types, making it the most broadly survival-associated NDST1-AS1 data layer.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher NDST1-AS1 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated NDST1-AS1 expression acts as an unfavorable survival marker, although some lineages such as LAML and LUAD show a favorable association.

UCEC, ACC, and KICH are the cancer types where NDST1-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	DFS	Quartile	III,IV	0.353	0.735	.001	72	view →
ACC	DFS	Median	II,III,IV	0.519	0.907	.003	39	view →
KICH	OS	Quartile	III,IV	0.204	1.000	.009	38	view →
LAML	DFS	Tertile	All	0.631	0.296	<.001	38	view →
READ	OS	Median	III,IV	0.403	0.955	<.001	33	view →
LUAD	OS	Tertile	All	0.870	0.740	.001	19	view →
CHOL	OS	Tertile	All	0.896	0.316	.013	18	view →
PAAD	OS	Median	All	0.465	0.196	.002	17	view →
STAD	OS	Quartile	All	0.231	0.474	.020	11	view →
THCA	DFS	Median	IV	0.457	0.865	.002	11	view →
SKCM	DFS	Tertile	II,III,IV	0.645	0.467	.009	7	view →
UCS	DFS	Quartile	II,III,IV	0.448	0.203	.048	6	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 22 lineages.

NDST1-AS1–UCEC (DFS)

Open the UCEC breakdown →