NDRG3

Across TCGA cell cohorts, NDRG3 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,258 significant associations in total. PANCREAS shows the largest number of these associations.

The most reproducible NDRG3-associated GO terms across cancer lineages are Protein localization to cilium, Centrosome separation, and Mitotic centrosome separation. Each is linked with NDRG3 in more than 10 cancer types. Because this analysis shows association rather than direction, both NDRG3-to-partner and partner-to-NDRG3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Protein localization to cilium grouped by NDRG3-low versus NDRG3-high in PANCREAS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NDRG3→partner) and Y-score (partner→NDRG3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	Protein localization to cilium →	+0.054	+0.745	<.001	<.001	3	11
BREAST	Centrosome separation →	+0.108	+0.826	.007	<.001	3	10
STOMACH	Mitotic centrosome separation →	+0.132	+0.680	<.001	<.001	3	9
KIDNEY	Positive regulation of chromosome segregation →	+0.151	+0.706	<.001	.005	3	8
BREAST	Regulation of centriole-centriole cohesion →	+0.127	+0.910	<.001	<.001	3	8
LIVER	UV-damage excision repair →	+0.141	+0.884	.005	.002	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,258 associations by consensus.

Protein localization to cilium by NDRG3 expression — PANCREAS

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