NDP-AS1

Across TCGA pan-cancer cohorts, NDP-AS1 RNA is linked to patient survival in 16 of 34 cancer types, making it the most broadly survival-associated NDP-AS1 data layer.

The strongest signal is observed in kidney chromophobe (KICH), where higher NDP-AS1 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated NDP-AS1 expression acts as an unfavorable survival marker, although some lineages such as UCEC and SKCM show a favorable association.

KICH, THCA, and UCEC are the cancer types where NDP-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KICH	OS	Tertile	All	0.155	0.926	<.001	63	view →
THCA	OS	Tertile	IV	0.095	0.966	<.001	57	view →
UCEC	OS	Median	All	0.957	0.902	.001	56	view →
READ	OS	Tertile	IV	0.370	0.798	<.001	54	view →
COAD	DFS	Tertile	II,III,IV	0.319	0.667	<.001	36	view →
ACC	OS	Tertile	III,IV	0.594	0.816	.036	27	view →
SKCM	OS	Tertile	III,IV	0.893	0.652	.012	24	view →
LGG	DFS	Quartile	All	0.771	0.894	.002	23	view →
LUAD	DFS	Tertile	All	0.524	0.695	.021	18	view →
ESCA	OS	Tertile	III,IV	0.669	0.317	.005	18	view →
CHOL	OS	Tertile	All	0.113	0.623	.040	18	view →
MESO	DFS	Tertile	II,III,IV	0.556	0.182	.031	12	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 16 lineages.

NDP-AS1–KICH (OS)

Open the KICH breakdown →