Across TCGA patient cohorts, NDOR1 mutation is significantly associated with the total protein of many other genes, with 20 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NDOR1-associated genes across cancer lineages are Smac, EGFR_pY1068, and EGFR_pY1173. Each is linked with NDOR1 in more than 1 cancer types. Because this analysis shows association rather than direction, both NDOR1-to-partner and partner-to-NDOR1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NDOR1→partner) and Y-score (partner→NDOR1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	Smac →	+0.277	+3.602	.032	.001	3	2
UCEC	EGFR_pY1068 →	-0.214	-2.222	.044	.011	3	1
UCEC	EGFR_pY1173 →	+0.080	+1.727	.018	.026	3	1
UCEC	HER3_pY1289 →	+0.076	+2.827	.038	.035	3	1
UCEC	JNK_pT183_Y185 →	-0.149	-2.209	.037	.011	3	1
UCEC	Ku80 →	+0.205	+2.179	.040	.034	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 20 associations by consensus.

Exploration

NDOR1 survival (RNA) · tumor vs normal (RNA) · all NDOR1 data types