NDN

Across TCGA pan-cancer cohorts, NDN mass-spec protein is linked to patient survival in 4 of 34 cancer types, making it a survival-associated NDN data layer compared with 21 for mass-spec protein and 11 for mutation status.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher NDN mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated NDN expression acts as an unfavorable survival marker.

UCEC, LSCC, and CCRCC are the cancer types where NDN mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	OS	Median	III,IV	0.433	1.000	.007	24	view →
LSCC	DFS	Quartile	All	0.552	0.815	.024	8	view →
CCRCC	DFS	Quartile	All	0.503	0.979	.004	6	view →
PDAC	DFS	Median	II,III,IV	0.289	0.658	.028	3	view →

Pink = unfavorable, green = favorable. Showing the 4 strongest of 4 lineages.

NDN–UCEC (OS)

Open the UCEC breakdown →