NDFIP2

Across TCGA cell cohorts, NDFIP2 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,635 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible NDFIP2-associated GO terms across cancer lineages are Positive regulation of translational initiation in response to stress, Regulation of IRE1-mediated unfolded protein response, and Response to topologically incorrect protein. Each is linked with NDFIP2 in more than 10 cancer types. Because this analysis shows association rather than direction, both NDFIP2-to-partner and partner-to-NDFIP2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of translational initiation in response to stress grouped by NDFIP2-low versus NDFIP2-high in PANCREAS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NDFIP2→partner) and Y-score (partner→NDFIP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	Positive regulation of translational initiation in response to stress →	+0.155	+1.315	<.001	<.001	3	11
BLOOD_Leukemia	Regulation of IRE1-mediated unfolded protein response →	+0.098	+1.968	<.001	<.001	3	10
STOMACH	Response to topologically incorrect protein →	+0.090	+1.226	.002	.008	3	10
LUNG_NSCLC_LUSC	IMP salvage →	-0.261	-0.934	<.001	.006	2	10
URINARY_TRACT	Regulation of ventricular cardiac muscle cell action potential →	+0.234	+1.380	<.001	<.001	3	9
STOMACH	Retrograde transport, vesicle recycling within Golgi →	+0.100	+1.047	.001	.003	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,635 associations by consensus.

Positive regulation of translational initiation in response to stress by NDFIP2 expression — PANCREAS

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