NDFIP1

Across TCGA patient cohorts, NDFIP1 mutation is significantly associated with the RNA expression of many other genes, with 2,042 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NDFIP1-associated genes across cancer lineages are MYO19, SNX3P1Y, and MRPL45. Each is linked with NDFIP1 in more than 1 cancer types. Because this analysis shows association rather than direction, both NDFIP1-to-partner and partner-to-NDFIP1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MYO19 grouped by NDFIP1-low versus NDFIP1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NDFIP1→partner) and Y-score (partner→NDFIP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MYO19 →	+0.520	+2.584	<.001	.001	3	1
UCEC	SNX3P1Y →	+0.084	+4.230	<.001	.004	3	1
UCEC	MRPL45 →	+0.507	+2.595	.009	<.001	3	1
UCEC	FAM219B →	+0.522	+2.595	<.001	.005	3	1
UCEC	PFAS →	+0.585	+2.815	<.001	.001	3	1
UCEC	ERICH3 →	-0.938	-3.542	.003	.002	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,042 associations by consensus.

MYO19 by NDFIP1 expression — UCEC

Explore this box plot interactively →