NDE1

Across TCGA patient cohorts, NDE1 RNA expression is significantly associated with the protein abundance of many other proteins, with 15,805 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible NDE1-associated proteins across cancer lineages are MCM2, ATAD2, and ATAD2_S327. Each is linked with NDE1 in more than 5 cancer types. Because this analysis shows association rather than direction, both NDE1-to-partner and partner-to-NDE1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, NDE1 versus MCM2 in OV, with a Pearson correlation of 0.34.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (NDE1→partner) and Y-score (partner→NDE1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	MCM2 →	+0.638	+0.640	<.001	.001	3	6
GBM	ATAD2 →	+0.488	+0.543	<.001	<.001	3	5
LSCC	ATAD2_S327 →	+0.802	+0.557	.003	.001	3	5
GBM	UHRF1 →	+0.737	+0.613	<.001	<.001	3	5
GBM	NCAPH →	+0.633	+0.550	<.001	<.001	3	5
OV	PCNA →	+0.562	+0.571	.001	.003	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,805 associations by consensus.

NDE1 vs MCM2 — OV

Explore this scatter interactively →