NDE1

Across TCGA patient cohorts, NDE1 protein abundance is significantly associated with the RNA expression of many other genes, with 7,361 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NDE1-associated genes across cancer lineages are HMOX2, LIMA1, and COL17A1. Each is linked with NDE1 in more than 4 cancer types. Because this analysis shows association rather than direction, both NDE1-to-partner and partner-to-NDE1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, NDE1 versus HMOX2 in UCEC, with a Pearson correlation of 0.37.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NDE1→partner) and Y-score (partner→NDE1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	HMOX2 →	+1.089	+0.301	<.001	<.001	3	5
BRCA	LIMA1 →	+0.721	+0.245	.003	<.001	3	4
LSCC	COL17A1 →	+1.559	+0.269	.002	.003	3	4
UCEC	ACTN1 →	+0.716	+0.289	<.001	<.001	3	4
UCEC	PPL →	+0.910	+0.198	.007	.009	3	4
UCEC	RHBDF1 →	+0.885	+0.238	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,361 associations by consensus.

NDE1 vs HMOX2 — UCEC

Explore this scatter interactively →