NDE1

Across TCGA cell cohorts, NDE1 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,102 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible NDE1-associated GO terms across cancer lineages are Regulation of mitotic cytokinesis, Mitotic spindle midzone assembly, and Regulation of metaphase/anaphase transition of cell cycle. Each is linked with NDE1 in more than 14 cancer types. Because this analysis shows association rather than direction, both NDE1-to-partner and partner-to-NDE1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of mitotic cytokinesis grouped by NDE1-low versus NDE1-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NDE1→partner) and Y-score (partner→NDE1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Regulation of mitotic cytokinesis →	+0.126	+1.365	<.001	<.001	3	15
SOFT_TISSUE	Mitotic spindle midzone assembly →	+0.255	+1.477	<.001	<.001	3	13
KIDNEY	Regulation of metaphase/anaphase transition of cell cycle →	+0.101	+0.796	<.001	<.001	3	13
SOFT_TISSUE	Microtubule cytoskeleton organization involved in mitosis →	+0.119	+1.535	<.001	<.001	3	13
PANCREAS	Positive regulation of mitotic cytokinesis →	+0.132	+1.107	<.001	<.001	3	13
SOFT_TISSUE	Mitotic spindle elongation →	+0.255	+1.477	<.001	<.001	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,102 associations by consensus.

Regulation of mitotic cytokinesis by NDE1 expression — SOFT_TISSUE

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