NDC80

Across TCGA patient cohorts, NDC80 protein abundance is significantly associated with the RNA expression of many other genes, with 20,247 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible NDC80-associated genes across cancer lineages are CDKN3, GINS1, and MYBL2. Each is linked with NDC80 in more than 7 cancer types. Because this analysis shows association rather than direction, both NDC80-to-partner and partner-to-NDC80 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, NDC80 versus CDKN3 in OV, with a Pearson correlation of 0.59.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NDC80→partner) and Y-score (partner→NDC80) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	CDKN3 →	+1.479	+0.609	<.001	<.001	3	8
LUAD	GINS1 →	+1.258	+0.861	<.001	<.001	3	8
LUAD	MYBL2 →	+1.864	+0.905	<.001	<.001	3	8
LUAD	E2F1 →	+1.301	+0.881	<.001	<.001	3	8
LUAD	CENPI →	+1.235	+0.838	<.001	<.001	3	8
UCEC	OIP5 →	+0.797	+0.537	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 20,247 associations by consensus.

NDC80 vs CDKN3 — OV

Explore this scatter interactively →