NDC80

Across TCGA patient cohorts, NDC80 protein abundance is significantly associated with the protein abundance of many other proteins, with 32,983 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible NDC80-associated proteins across cancer lineages are SMC2, TFDP1_S23, and WDHD1. Each is linked with NDC80 in more than 8 cancer types. Because this analysis shows association rather than direction, both NDC80-to-partner and partner-to-NDC80 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, NDC80 versus SMC2 in GBM, with a Pearson correlation of 0.93.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (NDC80→partner) and Y-score (partner→NDC80) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	SMC2 →	+0.886	+0.966	<.001	<.001	3	9
BRCA	TFDP1_S23 →	+1.212	+0.736	<.001	<.001	3	9
LUAD	WDHD1 →	+0.792	+0.784	<.001	<.001	3	9
LUAD	NUF2_S247 →	+1.456	+0.986	<.001	<.001	3	9
BRCA	MDC1 →	+0.513	+0.634	<.001	<.001	3	9
BRCA	MKI67 →	+0.988	+0.694	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 32,983 associations by consensus.

NDC80 vs SMC2 — GBM

Explore this scatter interactively →