NDC1

Across TCGA patient cohorts, NDC1 mutation is significantly associated with the RNA expression of many other genes, with 3,197 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NDC1-associated genes across cancer lineages are RNU6-1187P, PPP1R1AP2, and RNU5E-8P. Each is linked with NDC1 in more than 2 cancer types. Because this analysis shows association rather than direction, both NDC1-to-partner and partner-to-NDC1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNU6-1187P grouped by NDC1-low versus NDC1-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NDC1→partner) and Y-score (partner→NDC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	RNU6-1187P →	+0.164	+2.668	.009	.009	3	3
CESC	PPP1R1AP2 →	+0.159	+5.252	<.001	.002	3	2
HNSC	RNU5E-8P →	+0.515	+5.221	<.001	.003	3	2
CESC	RNU6-1085P →	+0.370	+3.705	<.001	.008	3	2
HNSC	LSP1P3 →	+0.423	+4.847	<.001	.002	3	2
HNSC	RNU6-1104P →	+0.296	+5.468	<.001	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,197 associations by consensus.

RNU6-1187P by NDC1 expression — SKCM

Explore this box plot interactively →