NDC1

Across TCGA cell cohorts, NDC1 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,010 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible NDC1-associated GO terms across cancer lineages are Nuclear pore localization, Sister chromatid cohesion, and DNA-templated DNA replication. Each is linked with NDC1 in more than 19 cancer types. Because this analysis shows association rather than direction, both NDC1-to-partner and partner-to-NDC1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Nuclear pore localization grouped by NDC1-low versus NDC1-high in OESOPHAGUS.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NDC1→partner) and Y-score (partner→NDC1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OESOPHAGUS	Nuclear pore localization →	+0.155	+0.884	<.001	<.001	3	20
OESOPHAGUS	Sister chromatid cohesion →	+0.098	+0.910	<.001	<.001	3	19
BONE	DNA-templated DNA replication →	+0.154	+1.311	.003	<.001	3	19
BONE	DNA replication initiation →	+0.239	+1.341	<.001	<.001	3	19
PANCREAS	Positive regulation of mitotic cell cycle phase transition →	+0.113	+1.037	<.001	<.001	3	19
SOFT_TISSUE	Nuclear pore organization →	+0.174	+1.034	<.001	<.001	3	18

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,010 associations by consensus.

Nuclear pore localization by NDC1 expression — OESOPHAGUS

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