NCS1

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, NCS1 protein abundance is significantly associated with the RNA expression of many other genes, with 14,159 significant associations in total. GBM shows the largest number of these associations.

The most reproducible NCS1-associated genes across cancer lineages are BMP1, TUBB6, and MFAP2. Each is linked with NCS1 in more than 6 cancer types. Because this analysis shows association rather than direction, both NCS1-to-partner and partner-to-NCS1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, NCS1 versus BMP1 in OV, with a Pearson correlation of 0.40.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NCS1→partner) and Y-score (partner→NCS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
OVBMP1 →+0.801+0.581.001<.00137
UCECTUBB6 →+1.169+0.580<.001<.00136
COADMFAP2 →+0.838+0.615<.001<.00135
OVPLAU →+1.648+0.516<.001.00626
HNSCGJA1 →+1.019+0.306.001.00135
HNSCARSI →+1.281+0.402<.001<.00135
Each partner links to its Q-omics profile. Showing the 6 strongest of 14,159 associations by consensus.

NCS1 vs BMP1 — OV

Per-sample scatter of NCS1 vs BMP1 in OV (Pearson r = 0.40).

Explore this scatter interactively →

Exploration