Across TCGA patient cohorts, NCR1 mutation is significantly associated with the RNA expression of many other genes, with 2,110 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible NCR1-associated genes across cancer lineages are PDSS1P2, PPP6R2, and SBF1. Each is linked with NCR1 in more than 2 cancer types. Because this analysis shows association rather than direction, both NCR1-to-partner and partner-to-NCR1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NCR1→partner) and Y-score (partner→NCR1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUSC	PDSS1P2 →	+0.137	+4.138	.001	.001	3	3
SKCM	PPP6R2 →	+0.332	+2.660	.002	.004	3	2
SKCM	SBF1 →	+0.393	+2.845	.006	.001	3	2
SKCM	JADE3 →	+0.462	+1.584	.006	.008	3	2
SKCM	CEP152 →	+0.441	+2.434	.003	.001	3	2
SKCM	DUS4L →	+0.389	+1.839	.004	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,110 associations by consensus.

Exploration

NCR1 survival (RNA) · tumor vs normal (RNA) · all NCR1 data types