Across TCGA cell cohorts, NCR1 mutation is significantly associated with the RNA expression of many other genes, with 36 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible NCR1-associated genes across cancer lineages are RGPD3, NXPH2, and ST8SIA3. Each is linked with NCR1 in more than 1 cancer types. Because this analysis shows association rather than direction, both NCR1-to-partner and partner-to-NCR1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NCR1→partner) and Y-score (partner→NCR1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	RGPD3 →	+0.167	+3.169	.002	.009	3	2
SKIN	NXPH2 →	+1.277	+2.874	<.001	.005	3	1
SKIN	ST8SIA3 →	+0.033	+2.688	<.001	.008	3	1
SKIN	RNF212 →	+1.924	+3.474	<.001	.003	3	1
SKIN	SLC35D3 →	+0.139	+2.716	<.001	.009	3	1
SKIN	SMTNL2 →	+0.242	+3.584	.004	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 36 associations by consensus.

Exploration

NCR1 survival (RNA) · tumor vs normal (RNA) · all NCR1 data types