Across TCGA patient cohorts, NCOR2 mutation is significantly associated with the RNA expression of many other genes, with 8,265 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NCOR2-associated genes across cancer lineages are POLE2, MND1, and NUSAP1. Each is linked with NCOR2 in more than 4 cancer types. Because this analysis shows association rather than direction, both NCOR2-to-partner and partner-to-NCOR2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NCOR2→partner) and Y-score (partner→NCOR2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	POLE2 →	+0.570	+2.631	.005	.005	3	5
UCEC	MND1 →	+0.674	+1.874	<.001	<.001	3	5
UCEC	NUSAP1 →	+0.676	+1.450	<.001	<.001	3	5
STAD	KIF11 →	+0.609	+3.725	.001	<.001	3	5
STAD	HPGDS →	-0.574	-3.894	.001	<.001	3	5
STAD	KIF15 →	+0.542	+1.847	.005	.008	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,265 associations by consensus.

Exploration

NCOR2 survival (RNA) · tumor vs normal (RNA) · all NCOR2 data types