Across TCGA patient cohorts, NCOR2 mutation is significantly associated with the total protein of many other genes, with 91 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NCOR2-associated genes across cancer lineages are Lck, Caspase-7-cleavedD198, and Cyclin-B1. Each is linked with NCOR2 in more than 3 cancer types. Because this analysis shows association rather than direction, both NCOR2-to-partner and partner-to-NCOR2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NCOR2→partner) and Y-score (partner→NCOR2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	Lck →	+0.258	+2.584	.004	.009	3	4
COAD	Caspase-7-cleavedD198 →	+0.980	+2.104	<.001	.002	3	4
UCEC	Cyclin-B1 →	+0.541	+1.544	<.001	<.001	3	4
STAD	c-Kit →	-0.245	-1.700	.043	.042	3	3
LUSC	PRAS40_pT246 →	+0.206	+3.179	.014	.010	3	3
UCEC	eEF2 →	+0.275	+1.652	.003	.005	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 91 associations by consensus.

Exploration

NCOR2 survival (RNA) · tumor vs normal (RNA) · all NCOR2 data types