Across TCGA cell cohorts, NCOR2 mutation is significantly associated with the RNA expression of many other genes, with 2,354 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible NCOR2-associated genes across cancer lineages are VPS37D, SYCE3, and TMEM82. Each is linked with NCOR2 in more than 3 cancer types. Because this analysis shows association rather than direction, both NCOR2-to-partner and partner-to-NCOR2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NCOR2→partner) and Y-score (partner→NCOR2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	VPS37D →	+0.592	+2.000	.001	.004	3	4
BLOOD_Leukemia	SYCE3 →	+0.534	+2.906	<.001	<.001	3	4
BLOOD_Lymphoma	TMEM82 →	+0.009	+3.058	<.001	.002	3	3
BLOOD_Leukemia	ARSA →	+0.755	+3.380	.002	.001	3	3
LARGE_INTESTINE	FBXO6 →	+1.148	+1.332	<.001	.001	3	3
LARGE_INTESTINE	PKD2 →	+0.806	+1.754	<.001	.005	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,354 associations by consensus.

Exploration

NCOR2 survival (RNA) · tumor vs normal (RNA) · all NCOR2 data types