NCOR1

Across TCGA pan-cancer cohorts, NCOR1 mass-spec protein is linked to patient survival in 3 of 34 cancer types, making it a survival-associated NCOR1 data layer compared with 26 for mass-spec protein and 8 for mutation status.

The strongest signal is observed in lung squamous cell carcinoma (LSCC), where higher NCOR1 mass-spec protein is associated with better overall survival. In most high-consensus cancer types, elevated NCOR1 expression acts as an unfavorable survival marker, although some lineages such as LSCC and PDAC show a favorable association.

LSCC, PDAC, and CCRCC are the cancer types where NCOR1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LSCC	OS	Quartile	All	1.000	0.738	.003	20	view →
PDAC	DFS	Quartile	All	0.960	0.641	.009	17	view →
CCRCC	DFS	Median	II,III,IV	1.000	0.268	.003	15	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

NCOR1–LSCC (OS)

Open the LSCC breakdown →