NCOA7-AS1

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, NCOA7-AS1 RNA is linked to patient survival in 13 of 34 cancer types, making it the most broadly survival-associated NCOA7-AS1 data layer.

The strongest signal is observed in cholangiocarcinoma (CHOL), where higher NCOA7-AS1 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated NCOA7-AS1 expression acts as an unfavorable survival marker, although some lineages such as MESO and UCS show a favorable association.

CHOL, CESC, and STAD are the cancer types where NCOA7-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
CHOLOSTertileIV0.0240.732.01436view →
CESCOSTertileIV0.1980.635.00636view →
STADDFSQuartileAll0.5920.847.00829view →
PRADDFSTertileAll0.8890.942.01618view →
SKCMOSTertileIV0.1920.571.00616view →
PAADDFSTertileAll0.2020.415.01112view →
KIRCOSQuartileII,III,IV0.5990.707.0188view →
MESOOSMedianIV0.7180.399.0206view →
UCSDFSTertileII,III,IV0.7490.366.0376view →
READOSTertileII,III,IV1.0000.581.0376view →
LGGDFSTertileAll0.6840.858.0243view →
THCADFSTertileIV1.0000.718.0343view →
Pink = unfavorable, green = favorable. Showing the 12 strongest of 13 lineages.

NCOA7-AS1–CHOL (OS)

Kaplan–Meier survival curve for NCOA7-AS1 RNA-high vs -low samples in CHOL.

Open the CHOL breakdown →

Exploration