Across TCGA patient cohorts, NCOA6 mutation is significantly associated with the RNA expression of many other genes, with 6,007 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NCOA6-associated genes across cancer lineages are MYDGF, PTH2, and GZMB. Each is linked with NCOA6 in more than 4 cancer types. Because this analysis shows association rather than direction, both NCOA6-to-partner and partner-to-NCOA6 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NCOA6→partner) and Y-score (partner→NCOA6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	MYDGF →	+0.419	+3.595	.003	.001	3	5
CESC	PTH2 →	+0.464	+3.142	.003	.004	3	4
LUAD	GZMB →	+1.329	+3.807	<.001	<.001	3	4
COAD	LINC02195 →	+1.101	+3.100	<.001	<.001	3	4
SKCM	MFSD12 →	+0.626	+1.803	.003	.006	3	4
UCEC	ABLIM2 →	-0.454	-1.392	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,007 associations by consensus.

Exploration

NCOA6 survival (RNA) · tumor vs normal (RNA) · all NCOA6 data types