Across TCGA patient cohorts, NCOA6 mutation is significantly associated with the total protein of many other genes, with 76 significant associations in total. COAD shows the largest number of these associations.

The most reproducible NCOA6-associated genes across cancer lineages are eIF4E, STAT3_pY705, and Fibronectin. Each is linked with NCOA6 in more than 3 cancer types. Because this analysis shows association rather than direction, both NCOA6-to-partner and partner-to-NCOA6 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NCOA6→partner) and Y-score (partner→NCOA6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	eIF4E →	+0.197	+1.749	.008	.049	3	4
UCEC	STAT3_pY705 →	-0.239	-1.174	<.001	.019	3	4
COAD	Fibronectin →	+0.488	+3.169	.023	.018	3	3
COAD	GAPDH →	+0.532	+1.882	.012	.031	3	3
LUAD	Caveolin-1 →	-0.698	-2.584	.030	.011	3	2
STAD	p90 RSK →	+0.307	+3.169	.013	.019	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 76 associations by consensus.

Exploration

NCOA6 survival (RNA) · tumor vs normal (RNA) · all NCOA6 data types