NCOA5

Across TCGA patient cohorts, NCOA5 mutation is significantly associated with the RNA expression of many other genes, with 3,917 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NCOA5-associated genes across cancer lineages are UBE2T, RTCB, and GTF2E1. Each is linked with NCOA5 in more than 2 cancer types. Because this analysis shows association rather than direction, both NCOA5-to-partner and partner-to-NCOA5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, UBE2T grouped by NCOA5-low versus NCOA5-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NCOA5→partner) and Y-score (partner→NCOA5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	UBE2T →	+0.658	+3.711	.001	<.001	3	3
UCEC	RTCB →	+0.426	+2.963	.007	<.001	3	3
UCEC	GTF2E1 →	+0.414	+3.364	.005	.004	3	2
UCEC	CCNB2 →	+0.591	+3.491	.007	.002	3	2
UCEC	SLC13A3 →	-0.547	-1.826	.003	.009	3	2
UCEC	GART →	+0.475	+1.858	.007	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,917 associations by consensus.

UBE2T by NCOA5 expression — UCEC

Explore this box plot interactively →