NCOA5

Across TCGA cell cohorts, NCOA5 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,087 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible NCOA5-associated GO terms across cancer lineages are Epigenetic regulation of gene expression, Positive regulation of double-strand break repair via homologous recombination, and Regulation of double-strand break repair via homologous recombination. Each is linked with NCOA5 in more than 17 cancer types. Because this analysis shows association rather than direction, both NCOA5-to-partner and partner-to-NCOA5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Epigenetic regulation of gene expression grouped by NCOA5-low versus NCOA5-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NCOA5→partner) and Y-score (partner→NCOA5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Epigenetic regulation of gene expression →	+0.074	+0.967	<.001	<.001	3	18
BONE	Positive regulation of double-strand break repair via homologous recombination →	+0.098	+0.721	<.001	.003	3	18
BONE	Regulation of double-strand break repair via homologous recombination →	+0.136	+1.072	<.001	<.001	3	17
STOMACH	RNA export from nucleus →	+0.141	+0.810	<.001	<.001	3	17
STOMACH	mRNA export from nucleus →	+0.134	+0.941	<.001	<.001	3	17
STOMACH	Nucleocytoplasmic transport →	+0.078	+1.009	.001	<.001	3	17

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,087 associations by consensus.

Epigenetic regulation of gene expression by NCOA5 expression — SOFT_TISSUE

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