NCOA2

Across TCGA patient cohorts, NCOA2 RNA expression is significantly associated with the protein abundance of many other proteins, with 13,750 significant associations in total. PDAC shows the largest number of these associations.

The most reproducible NCOA2-associated proteins across cancer lineages are NCOA2_S579, NCOA2_S699, and NCOA2_S493. Each is linked with NCOA2 in more than 7 cancer types. Because this analysis shows association rather than direction, both NCOA2-to-partner and partner-to-NCOA2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, NCOA2 versus NCOA2_S579 in LUAD, with a Pearson correlation of 0.47.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (NCOA2→partner) and Y-score (partner→NCOA2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUAD	NCOA2_S579 →	+0.698	+0.370	<.001	<.001	3	8
BRCA	NCOA2_S699 →	+0.601	+1.137	<.001	<.001	3	8
BRCA	NCOA2_S493 →	+0.444	+0.651	<.001	<.001	3	6
BRCA	VCPIP1 →	+0.403	+0.806	<.001	<.001	3	6
LUAD	NCOA2_S29 →	+0.418	+0.639	<.001	<.001	3	5
BRCA	NCOA2_S736 →	+1.052	+0.765	<.001	.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 13,750 associations by consensus.

NCOA2 vs NCOA2_S579 — LUAD

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