NCOA2

Across TCGA patient cohorts, NCOA2 mutation is significantly associated with the RNA expression of many other genes, with 4,101 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NCOA2-associated genes across cancer lineages are TAF9, SSRP1, and FANCC. Each is linked with NCOA2 in more than 3 cancer types. Because this analysis shows association rather than direction, both NCOA2-to-partner and partner-to-NCOA2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TAF9 grouped by NCOA2-low versus NCOA2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NCOA2→partner) and Y-score (partner→NCOA2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	TAF9 →	+0.630	+1.784	<.001	<.001	3	4
UCEC	SSRP1 →	+0.414	+2.102	.001	<.001	3	4
UCEC	FANCC →	+0.461	+2.769	<.001	<.001	3	4
UCEC	PKN3 →	+0.919	+2.513	<.001	<.001	3	4
UCEC	SNRNP25 →	+0.482	+2.882	<.001	<.001	3	4
UCEC	H2AZ1 →	+0.593	+1.816	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,101 associations by consensus.

TAF9 by NCOA2 expression — UCEC

Explore this box plot interactively →