NCOA2

Across TCGA cell cohorts, NCOA2 mutation is significantly associated with the RNA expression of many other genes, with 839 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible NCOA2-associated genes across cancer lineages are IFNA14, CDK2AP1, and ARL1. Each is linked with NCOA2 in more than 1 cancer types. Because this analysis shows association rather than direction, both NCOA2-to-partner and partner-to-NCOA2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, IFNA14 grouped by NCOA2-low versus NCOA2-high in BREAST.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NCOA2→partner) and Y-score (partner→NCOA2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	IFNA14 →	+0.027	+4.781	<.001	.003	3	2
LARGE_INTESTINE	CDK2AP1 →	+0.649	+3.321	.001	.003	3	2
LARGE_INTESTINE	ARL1 →	+0.520	+2.626	<.001	.001	3	2
LARGE_INTESTINE	HUS1 →	+0.379	+2.244	.006	.003	3	2
LARGE_INTESTINE	GTF2B →	+0.327	+2.005	.004	.008	3	2
LARGE_INTESTINE	SLC30A9 →	+0.473	+3.082	<.001	.007	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 839 associations by consensus.

IFNA14 by NCOA2 expression — BREAST

Explore this box plot interactively →