NCMAP

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, NCMAP RNA expression is significantly associated with the go_rna of many other GO terms, with 1,835 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible NCMAP-associated GO terms across cancer lineages are Cellular response to alcohol, Establishment of apical/basal cell polarity, and Vesicle localization. Each is linked with NCMAP in more than 7 cancer types. Because this analysis shows association rather than direction, both NCMAP-to-partner and partner-to-NCMAP results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NCMAP→partner) and Y-score (partner→NCMAP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LUNG_NSCLC_LUADCellular response to alcohol →+0.088+1.063<.001.00138
PANCREASEstablishment of apical/basal cell polarity →-0.158-0.549.001.00337
BREASTVesicle localization →+0.051+0.869<.001.00237
LUNG_NSCLC_LUADResponse to indole-3-methanol →+0.178+0.891<.001<.00136
LUNG_NSCLC_LUADBundle of His cell to Purkinje myocyte communication →+0.241+0.912.007.00136
LUNG_NSCLC_LUADPositive regulation of establishment of T cell polarity →-0.154-0.818<.001.00136
Each partner links to its Q-omics profile. Showing the 6 strongest of 1,835 associations by consensus.

Exploration