NCLN

Across TCGA cell cohorts, NCLN RNA expression is significantly associated with the RNA expression of many other genes, with 10,194 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible NCLN-associated genes across cancer lineages are THOP1, PSMD2, and DOHH. Each is linked with NCLN in more than 18 cancer types. Because this analysis shows association rather than direction, both NCLN-to-partner and partner-to-NCLN results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, NCLN versus THOP1 in SKIN, with a Pearson correlation of 0.83.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NCLN→partner) and Y-score (partner→NCLN) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	THOP1 →	+1.350	+0.926	<.001	<.001	3	19
URINARY_TRACT	PSMD2 →	+1.317	+1.111	<.001	<.001	3	18
SOFT_TISSUE	DOHH →	+1.309	+1.128	<.001	<.001	3	17
LIVER	CACTIN →	+1.091	+1.007	.001	<.001	3	17
BLOOD_Lymphoma	EIF4G1 →	+0.856	+0.773	<.001	<.001	3	17
PANCREAS	TCOF1 →	+1.019	+0.696	<.001	<.001	3	17

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,194 associations by consensus.

NCLN vs THOP1 — SKIN

Explore this scatter interactively →