NCKAP5

Across TCGA patient cohorts, NCKAP5 mutation is significantly associated with the RNA expression of many other genes, with 8,051 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NCKAP5-associated genes across cancer lineages are PSMD9, CEP55, and CENPW. Each is linked with NCKAP5 in more than 5 cancer types. Because this analysis shows association rather than direction, both NCKAP5-to-partner and partner-to-NCKAP5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PSMD9 grouped by NCKAP5-low versus NCKAP5-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NCKAP5→partner) and Y-score (partner→NCKAP5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	PSMD9 →	+0.322	+1.415	<.001	<.001	3	6
STAD	CEP55 →	+0.712	+3.700	<.001	.001	3	6
STAD	CENPW →	+0.606	+2.264	.001	.001	3	6
COAD	NCAPH →	+0.483	+3.920	<.001	<.001	3	6
UCEC	PIMREG →	+0.659	+1.328	<.001	<.001	3	6
LUAD	RBPMS →	-0.489	-3.688	.004	.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,051 associations by consensus.

PSMD9 by NCKAP5 expression — UCEC

Explore this box plot interactively →