NCKAP5

Across TCGA cell cohorts, NCKAP5 mutation is significantly associated with the RNA expression of many other genes, with 1,327 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible NCKAP5-associated genes across cancer lineages are C16orf90, DBX2, and TRIM49C. Each is linked with NCKAP5 in more than 1 cancer types. Because this analysis shows association rather than direction, both NCKAP5-to-partner and partner-to-NCKAP5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, C16orf90 grouped by NCKAP5-low versus NCKAP5-high in SOFT_TISSUE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NCKAP5→partner) and Y-score (partner→NCKAP5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	C16orf90 →	+0.030	+4.417	.007	.004	3	2
OESOPHAGUS	DBX2 →	+0.045	+3.836	<.001	.004	3	2
OESOPHAGUS	TRIM49C →	+0.202	+3.836	<.001	.004	3	2
KIDNEY	KRT6C →	+0.006	+5.000	<.001	.005	3	2
LUNG_NSCLC_LUAD	EEF1E1 →	+0.497	+3.584	.001	<.001	3	2
LARGE_INTESTINE	SLC25A1 →	+0.671	+1.458	<.001	.009	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,327 associations by consensus.

C16orf90 by NCKAP5 expression — SOFT_TISSUE

Explore this box plot interactively →