NCKAP5-IT1

Across TCGA pan-cancer cohorts, NCKAP5-IT1 RNA is linked to patient survival in 17 of 34 cancer types, making it the most broadly survival-associated NCKAP5-IT1 data layer.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where higher NCKAP5-IT1 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated NCKAP5-IT1 expression acts as an unfavorable survival marker, although some lineages such as LGG and OV show a favorable association.

HNSC, LAML, and COAD are the cancer types where NCKAP5-IT1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
HNSC	OS	Quartile	All	0.302	0.495	.007	43	view →
LAML	DFS	Tertile	All	0.269	0.585	.009	36	view →
COAD	DFS	Tertile	II,III,IV	0.283	0.659	.002	27	view →
BLCA	DFS	Tertile	All	0.512	0.629	.024	24	view →
LGG	OS	Tertile	All	0.933	0.836	.001	23	view →
OV	DFS	Tertile	All	0.279	0.144	.025	18	view →
SKCM	DFS	Tertile	III,IV	0.384	0.681	.016	12	view →
PCPG	OS	Tertile	All	0.944	1.000	.045	9	view →
READ	OS	Tertile	III,IV	0.328	0.751	.003	9	view →
KIRC	DFS	Median	IV	0.630	0.313	.014	8	view →
THYM	DFS	Tertile	All	0.264	0.752	.011	6	view →
THCA	OS	Tertile	All	0.713	0.958	.009	6	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 17 lineages.

NCKAP5-IT1–HNSC (OS)

Open the HNSC breakdown →