NCKAP5-AS1

Across TCGA pan-cancer cohorts, NCKAP5-AS1 RNA is linked to patient survival in 16 of 34 cancer types, making it the most broadly survival-associated NCKAP5-AS1 data layer.

The strongest signal is observed in cholangiocarcinoma (CHOL), where higher NCKAP5-AS1 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated NCKAP5-AS1 expression acts as an unfavorable survival marker, although some lineages such as ESCA and KIRP show a favorable association.

CHOL, ESCA, and HNSC are the cancer types where NCKAP5-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CHOL	OS	Tertile	All	0.024	0.675	<.001	72	view →
ESCA	DFS	Quartile	All	0.840	0.302	.012	33	view →
HNSC	OS	Median	All	0.695	0.781	.003	33	view →
READ	DFS	Tertile	III,IV	0.082	0.749	<.001	27	view →
THYM	OS	Tertile	All	0.812	0.983	.005	18	view →
UCS	DFS	Tertile	II,III,IV	0.160	0.463	.019	18	view →
LUAD	DFS	Tertile	IV	0.140	0.603	.021	18	view →
KIRP	DFS	Tertile	II,III,IV	1.000	0.454	.040	12	view →
THCA	DFS	Tertile	All	0.974	0.812	.036	12	view →
SKCM	DFS	Tertile	IV	0.074	0.497	.024	9	view →
BLCA	OS	Tertile	IV	0.414	0.606	.036	6	view →
OV	DFS	Median	IV	0.227	0.380	.034	6	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 16 lineages.

NCKAP5-AS1–CHOL (OS)

Open the CHOL breakdown →