NCKAP1L

Across TCGA pan-cancer cohorts, NCKAP1L mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated NCKAP1L data layer compared with 25 for mass-spec protein and 7 for mutation status.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where higher NCKAP1L mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated NCKAP1L expression acts as an unfavorable survival marker, although some lineages such as LUAD show a favorable association.

CCRCC, PDAC, and LUAD are the cancer types where NCKAP1L mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CCRCC	OS	Quartile	All	0.726	0.991	.008	11	view →
PDAC	DFS	Tertile	II,III,IV	0.662	0.923	.010	8	view →
LUAD	DFS	Quartile	All	0.787	0.376	.007	8	view →
HNSC	DFS	Median	All	0.923	0.979	.039	2	view →
GBM	OS	Median	All	0.459	0.617	.028	2	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

NCKAP1L–CCRCC (OS)

Open the CCRCC breakdown →