NCKAP1L

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, NCKAP1L protein abundance is significantly associated with the RNA expression of many other genes, with 19,200 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible NCKAP1L-associated genes across cancer lineages are CYTH4, APOBEC3H, and NCF4. Each is linked with NCKAP1L in more than 8 cancer types. Because this analysis shows association rather than direction, both NCKAP1L-to-partner and partner-to-NCKAP1L results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, NCKAP1L versus CYTH4 in GBM, with a Pearson correlation of 0.85.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NCKAP1L→partner) and Y-score (partner→NCKAP1L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
GBMCYTH4 →+1.278+0.822<.001<.00139
OVAPOBEC3H →+0.791+0.455<.001<.00139
GBMNCF4 →+1.249+0.822<.001<.00139
GBMCSF2RB →+1.237+0.847<.001<.00139
BRCAIL2RB →+1.169+0.441<.001<.00139
BRCASLA2 →+0.987+0.498<.001<.00139
Each partner links to its Q-omics profile. Showing the 6 strongest of 19,200 associations by consensus.

NCKAP1L vs CYTH4 — GBM

Per-sample scatter of NCKAP1L vs CYTH4 in GBM (Pearson r = 0.85).

Explore this scatter interactively →

Exploration