NCKAP1L

Across TCGA cell cohorts, NCKAP1L RNA expression is significantly associated with the go_rna of many other GO terms, with 4,012 significant associations in total. BONE shows the largest number of these associations.

The most reproducible NCKAP1L-associated GO terms across cancer lineages are Nucleic acid catabolic process, Regulation of aggrephagy, and Response to gamma radiation. Each is linked with NCKAP1L in more than 8 cancer types. Because this analysis shows association rather than direction, both NCKAP1L-to-partner and partner-to-NCKAP1L results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Nucleic acid catabolic process grouped by NCKAP1L-low versus NCKAP1L-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NCKAP1L→partner) and Y-score (partner→NCKAP1L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Nucleic acid catabolic process →	+0.069	+4.582	<.001	<.001	3	9
BLOOD_Lymphoma	Regulation of aggrephagy →	+0.113	+1.698	<.001	<.001	3	9
LUNG_NSCLC_LUAD	Response to gamma radiation →	+0.046	+0.050	.001	.008	3	8
BLOOD_Leukemia	Protein polymerization →	+0.059	+0.658	<.001	<.001	3	8
LARGE_INTESTINE	Protein sumoylation →	+0.051	+0.144	<.001	.002	3	7
BONE	Regulation of transcription of nucleolar large rRNA by RNA polymerase I →	+0.125	+2.932	.001	.006	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,012 associations by consensus.

Nucleic acid catabolic process by NCKAP1L expression — BONE

Explore this box plot interactively →