NCF4

Across TCGA pan-cancer cohorts, NCF4 Mutation is linked to patient survival in 3 of 34 cancer types, making it a survival-associated NCF4 data layer compared with 28 for mass-spec protein and 7 for mass-spec protein.

The strongest signal is observed in bladder urothelial carcinoma (BLCA), where higher NCF4 Mutation is associated with worse disease-free survival. In most high-consensus cancer types, elevated NCF4 expression acts as an unfavorable survival marker.

BLCA, PRAD, and LGG are the cancer types where NCF4 Mutation most reproducibly stratifies survival.

Mutation survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
BLCA	DFS	Median	All	0.015	0.594	<.001	6	view →
PRAD	DFS	Median	All	0.645	0.936	.010	4	view →
LGG	OS	Median	All	0.291	0.810	.046	3	view →

Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

NCF4–BLCA (DFS)

Open the BLCA breakdown →