NCF4

Across TCGA patient cohorts, NCF4 protein abundance is significantly associated with the RNA expression of many other genes, with 20,941 significant associations in total. GBM shows the largest number of these associations.

The most reproducible NCF4-associated genes across cancer lineages are CYTH4, CSF2RB, and SIRPB1. Each is linked with NCF4 in more than 9 cancer types. Because this analysis shows association rather than direction, both NCF4-to-partner and partner-to-NCF4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, NCF4 versus CYTH4 in GBM, with a Pearson correlation of 0.69.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NCF4→partner) and Y-score (partner→NCF4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	CYTH4 →	+1.055	+0.696	<.001	<.001	3	10
GBM	CSF2RB →	+1.100	+0.798	<.001	<.001	3	10
UCEC	SIRPB1 →	+0.766	+0.619	<.001	<.001	3	10
GBM	TLR8 →	+1.071	+0.687	<.001	<.001	3	10
BRCA	IL4I1 →	+1.415	+0.500	<.001	<.001	3	10
GBM	LILRB1 →	+0.847	+0.694	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 20,941 associations by consensus.

NCF4 vs CYTH4 — GBM

Explore this scatter interactively →